Apoptosis-mediated antiproliferation of A549 lung cancer cells mediated by Eugenia aquea leaf compound 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone and its molecular interaction with caspase receptor in molecular docking simulation

In a previous study, 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (ChalcEA) isolated from the leaves of Eugenia aquea was reported to inhibit proliferation of the breast adenocarcinoma MCF7 cell line and to promote apoptosis via activation of poly(adenosine diphosphate-ribose) polymerase protei...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Hadisaputri, Yuni Elsa, Cahyana, Noni, Muchtaridi, Muchtaridi, Lesmana, Ronny, Rusdiana, Taofik, Chaerunisa, Anis Yohana, Sufiawati, Irna, Rostinawati, Tina, Subarnas, Anas
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115064/
https://ncbi.nlm.nih.gov/pubmed/32269629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11466
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