Mal protein stabilizes luminal membrane PLC-β3 and negatively regulates ENaC in mouse cortical collecting duct cells

Abnormally high epithelial Na(+) channel (ENaC) activity in the aldosterone-sensitive distal nephron and collecting duct leads to hypertension. Myelin and lymphocyte (Mal) is a lipid raft-associated protein that has been previously shown to regulate Na(+)-K-2Cl(−) cotransporter and aquaporin-2 in th...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Tuna, Kubra M., Liu, Bing-Chen, Yue, Qiang, Ghazi, Zinah M., Ma, He-Ping, Eaton, Douglas C., Alli, Abdel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843038/
https://ncbi.nlm.nih.gov/pubmed/31364376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00446.2018
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