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Role of apoptotic hepatocytes in HCV dissemination: regulation by acetaldehyde

Alcohol consumption exacerbates hepatitis C virus (HCV) pathogenesis and promotes disease progression, although the mechanisms are not quite clear. We have previously observed that acetaldehyde (Ach) continuously produced by the acetaldehyde-generating system (AGS), temporarily enhanced HCV RNA leve...

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Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Ganesan, Murali, Natarajan, Sathish Kumar, Zhang, Jinjin, Mott, Justin L., Poluektova, Larisa I., McVicker, Benita L., Kharbanda, Kusum K., Tuma, Dean J., Osna, Natalia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842882/
https://ncbi.nlm.nih.gov/pubmed/27056722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00021.2016
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