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Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus Infected Liver Cells by Up-Regulating USP18

BACKGROUND: Alcohol consumption exacerbates the pathogenesis of HCV-infection and worsens disease outcomes. The exact reasons are not clear yet, but they might be partially attributed to the ability of alcohol to further suppress innate immunity. Innate immunity is known to be already decreased by H...

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Dades bibliogràfiques
Publicat a:Alcohol Clin Exp Res
Autors principals: Ganesan, Murali, Poluektova, Larisa Y., Tuma, Dean J., Kharbanda, Kusum K., Osna, Natalia A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800117/
https://ncbi.nlm.nih.gov/pubmed/27716962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13226
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