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Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus Infected Liver Cells by Up-Regulating USP18

BACKGROUND: Alcohol consumption exacerbates the pathogenesis of HCV-infection and worsens disease outcomes. The exact reasons are not clear yet, but they might be partially attributed to the ability of alcohol to further suppress innate immunity. Innate immunity is known to be already decreased by H...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Ganesan, Murali, Poluektova, Larisa Y., Tuma, Dean J., Kharbanda, Kusum K., Osna, Natalia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800117/
https://ncbi.nlm.nih.gov/pubmed/27716962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13226
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