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Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation

The major source of ATP in cancer cells remains unclear. Here, we examined energy metabolism in gastric cancer cells and found increased fatty acid oxidation and increased expression of ALDH3A1. Metabolic analysis showed that lipid peroxidation by reactive oxygen species led to spontaneous productio...

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Publicat a:Sci Rep
Autors principals: Lee, Jae-Seon, Kim, Seung Hwa, Lee, Soohyun, Kang, Joon Hee, Lee, Seon-Hyeong, Cheong, Jae-Ho, Kim, Soo-Youl
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841934/
https://ncbi.nlm.nih.gov/pubmed/31705020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52814-1
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