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Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation

The major source of ATP in cancer cells remains unclear. Here, we examined energy metabolism in gastric cancer cells and found increased fatty acid oxidation and increased expression of ALDH3A1. Metabolic analysis showed that lipid peroxidation by reactive oxygen species led to spontaneous productio...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Lee, Jae-Seon, Kim, Seung Hwa, Lee, Soohyun, Kang, Joon Hee, Lee, Seon-Hyeong, Cheong, Jae-Ho, Kim, Soo-Youl
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841934/
https://ncbi.nlm.nih.gov/pubmed/31705020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52814-1
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