Active DNA unwinding and transport by a membrane-adapted helicase nanopore

Nanoscale transport through nanopores and live-cell membranes plays a vital role in both key biological processes as well as biosensing and DNA sequencing. Active translocation of DNA through these nanopores usually needs enzyme assistance. Here we present a nanopore derived from truncated helicase...

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Published in:Nat Commun
Main Authors: Sun, Ke, Zhao, Changjian, Zeng, Xiaojun, Chen, Yuejia, Jiang, Xin, Ding, Xianting, Gou, Lu, Xie, Haiyang, Li, Xinqiong, Zhang, Xialin, Lin, Sheng, Dou, Linqin, Wei, Long, Niu, Haofu, Zhang, Ming, Tian, Ruocen, Sawyer, Erica, Yuan, Qingyue, Huang, Yuqin, Chen, Piaopiao, Zhao, Chengjian, Zhou, Cuisong, Ying, Binwu, Shi, Bingyang, Wei, Xiawei, Jiang, Ruotian, Zhang, Lei, Lu, Guangwen, Geng, Jia
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841704/
https://ncbi.nlm.nih.gov/pubmed/31704937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13047-y
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