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Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency

Truncating variants in TTN (TTNtv), coding for the largest structural protein in the sarcomere, contribute to the largest portion of familial and ambulatory dilated cardiomyopathy (DCM). TTN haploinsufficiency caused by TTNtv is suggested as the disease mechanism. However, it is unclear whether TTN...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Liao, Dan, Chen, Weiming, Tan, Chia Yee, Wong, Jing Xuan, Chan, Pui Shi, Tan, Lek Wen, Foo, Roger, Jiang, Jianming
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841687/
https://ncbi.nlm.nih.gov/pubmed/31705051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52796-0
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