Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf

RATIONALE: Pathogenic variations in the lamin gene (LMNA) cause familial dilated cardiomyopathy (DCM). LMNA insufficiency caused by LMNA pathogenic variants is believed to be the basic mechanism underpinning LMNA-related DCM. OBJECTIVE: To assess whether silencing of cardiac Lmna causes DCM and inve...

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Udgivet i:Circ Res
Main Authors: Tan, Chia Yee, Wong, Jing Xuan, Chan, Pui Shi, Tan, Hansen, Liao, Dan, Chen, Weiming, Tan, Lek Wen, Ackers-Johnson, Matthew, Wakimoto, Hiroko, Seidman, Jonathan G., Seidman, Christine E., Lunde, Ida Gjervold, Zhu, Feng, Hu, Qidong, Bian, Jinsong, Wang, Jiong-Wei, Foo, Roger S., Jiang, Jianming
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336364/
https://ncbi.nlm.nih.gov/pubmed/31495264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.314794
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