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Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency
Truncating variants in TTN (TTNtv), coding for the largest structural protein in the sarcomere, contribute to the largest portion of familial and ambulatory dilated cardiomyopathy (DCM). TTN haploinsufficiency caused by TTNtv is suggested as the disease mechanism. However, it is unclear whether TTN...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6841687/ https://ncbi.nlm.nih.gov/pubmed/31705051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52796-0 |
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