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SEX AND TISSUE SPECIFIC ROLES OF MTORC2 IN HEALTHSPAN, METABOLISM, AND SURVIVAL
Genetic and pharmacological inhibition of the mechanistic Target Of Rapamycin Complex 1 (mTORC1) promotes health and longevity in organisms ranging from yeast to mice, and may also have rejuvenative effects in dogs and humans. A potential barrier to the translation of rapamycin-based therapies to th...
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| Publicado no: | Innov Aging |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6840699/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.1351 |
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