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Set-up and screening of a fragment library targeting the 14-3-3 protein interface
Protein–protein interactions (PPIs) are at the core of regulation mechanisms in biological systems and consequently became an attractive target for therapeutic intervention. PPIs involving the adapter protein 14-3-3 are representative examples given the broad range of partner proteins forming a comp...
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| Pubblicato in: | Medchemcomm |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6839876/ https://ncbi.nlm.nih.gov/pubmed/31814953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00215d |
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