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The Prolyl Isomerase Pin1 Controls Lipopolysaccharide-Induced Priming of NADPH Oxidase in Human Neutrophils

Production of superoxide anion and other reactive oxygen species (ROS) by neutrophils has a vital role in host defense against microbes. However, over-production can induce cell injury participating to inflammation. Superoxide anion is produced by the phagocyte NADPH oxidase/NOX2, a multicomponent e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Liu, Min, Bedouhene, Samia, Hurtado-Nedelec, Margarita, Pintard, Coralie, Dang, Pham My-chan, Yu, Shiyuan, El-Benna, Jamel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839773/
https://ncbi.nlm.nih.gov/pubmed/31736979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02567
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