Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease

Aging-related neurodegenerative disorders are frequently associated with the aggregation of multiple amyloidogenic proteins (APs), although the reason why such detrimental phenomena have emerged in the post-reproductive human brain across evolution is unclear. Speculatively, APs might provide physio...

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Bibliographic Details
Published in:J Parkinsons Dis
Main Authors: Hashimoto, Makoto, Ho, Gilbert, Takamatsu, Yoshiki, Wada, Ryoko, Sugama, Shuei, Takenouchi, Takato, Waragai, Masaaki, Masliah, Eliezer
Format: Artigo
Language:Inglês
Published: IOS Press 2019
Subjects:
Hypothesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839461/
https://ncbi.nlm.nih.gov/pubmed/31524179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-191675
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