Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates

At present, the precise physiological role of neurodegenerative disease-related amyloidogenic proteins (APs), including α-synuclein in Parkinson’s disease and β-amyloid in Alzheimer’s disease, remains unclear. Because of similar adaptability of both human brain neurons and yeast cells to diverse env...

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Dettagli Bibliografici
Pubblicato in:J Parkinsons Dis
Autori principali: Hashimoto, Makoto, Ho, Gilbert, Takamatsu, Yoshiki, Shimizu, Yuka, Sugama, Shuei, Takenouchi, Takato, Waragai, Masaaki, Masliah, Eliezer
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2018
Soggetti:
Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130413/
https://ncbi.nlm.nih.gov/pubmed/30010144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-181365
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