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Possible Role of the Polyglutamine Elongation in Evolution of Amyloid-Related Evolvability
The polyglutamine (polyQ) diseases, such as Huntington’s disease and the spinocerebellar ataxias, are characterized by the accumulation of elongated polyQ sequences (epolyQ) and mostly occur during midlife. Considering that polyQ disorders have not been selected out in evolution, there might be impo...
Uloženo v:
| Vydáno v: | J Huntingtons Dis |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
IOS Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294593/ https://ncbi.nlm.nih.gov/pubmed/30372687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180309 |
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