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Zinc-finger protein p52-ZER6 accelerates colorectal cancer cell proliferation and tumour progression through promoting p53 ubiquitination

BACKGROUND: Aberrant expression of p53 and its downstream gene p21 is closely related to alterations in cell cycle and cell proliferation, and is common among cancer patients. However, the underlying molecular mechanism has not been fully unravelled. ZER6 is a zinc-finger protein with two isoforms p...

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Publicado en:EBioMedicine
Main Authors: Huang, Can, Wu, Shourong, Li, Wenfang, Herkilini, Arin, Miyagishi, Makoto, Zhao, Hezhao, Kasim, Vivi
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838388/
https://ncbi.nlm.nih.gov/pubmed/31521611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.070
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