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Determination of the Role of DDX3 a Factor Involved in Mammalian RNAi Pathway Using an shRNA-Expression Library

RNA interference (RNAi) is an endogenous RNA-destruction phenomenon induced by certain double-stranded RNAs (dsRNAs). In RNAi, dsRNAs are processed into small interfering RNAs (siRNAs) which in turn trigger the cleavage of the target mRNA. Here, using a short hairpin RNA-expression library, we ident...

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Detalhes bibliográficos
Main Authors: Kasim, Vivi, Wu, Shourong, Taira, Kazunari, Miyagishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602433/
https://ncbi.nlm.nih.gov/pubmed/23527197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059445
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