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Effects on RNAi of the tight structure, sequence and position of the targeted region

RNA interference (RNAi) is a gene-silencing phenomenon that involves the double-stranded RNA-mediated cleavage of mRNA, and small interfering RNAs (siRNAs) can cause RNAi in mammalian cells. There have been many attempts to clarify the mechanism of RNAi, but information about the relationship betwee...

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Detalhes bibliográficos
Main Authors: Yoshinari, Koichi, Miyagishi, Makoto, Taira, Kazunari
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373345/
https://ncbi.nlm.nih.gov/pubmed/14762201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh221
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