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Effects on RNAi of the tight structure, sequence and position of the targeted region

RNA interference (RNAi) is a gene-silencing phenomenon that involves the double-stranded RNA-mediated cleavage of mRNA, and small interfering RNAs (siRNAs) can cause RNAi in mammalian cells. There have been many attempts to clarify the mechanism of RNAi, but information about the relationship betwee...

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Autores principales: Yoshinari, Koichi, Miyagishi, Makoto, Taira, Kazunari
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC373345/
https://ncbi.nlm.nih.gov/pubmed/14762201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh221
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