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Zinc-finger protein p52-ZER6 accelerates colorectal cancer cell proliferation and tumour progression through promoting p53 ubiquitination

BACKGROUND: Aberrant expression of p53 and its downstream gene p21 is closely related to alterations in cell cycle and cell proliferation, and is common among cancer patients. However, the underlying molecular mechanism has not been fully unravelled. ZER6 is a zinc-finger protein with two isoforms p...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Huang, Can, Wu, Shourong, Li, Wenfang, Herkilini, Arin, Miyagishi, Makoto, Zhao, Hezhao, Kasim, Vivi
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838388/
https://ncbi.nlm.nih.gov/pubmed/31521611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.070
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