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Genetic determinants of responsiveness to mesenchymal stem cell injections in non-ischemic dilated cardiomyopathy

BACKGROUND: Non-ischemic dilated cardiomyopathy (NIDCM) responds variably to intramyocardial injection of mesenchymal stem cells (MSCs). We hypothesized that NIDCM genotype may influence responsiveness to MSC therapy and performed genotyping on all patients in the POSEIDON-DCM trial. METHODS: POSEID...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Rieger, Angela C., Myerburg, Robert J., Florea, Victoria, Tompkins, Bryon A., Natsumeda, Makoto, Premer, Courtney, Khan, Aisha, Schulman, Ivonne H., Vidro-Casiano, Mayra, DiFede, Darcy L., Heldman, Alan W., Mitrani, Raul, Hare, Joshua M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838383/
https://ncbi.nlm.nih.gov/pubmed/31648988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.043
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