Mesenchymal Stem Cell Secretion of SDF-1α Modulates Endothelial Function in Dilated Cardiomyopathy

BACKGROUND: Endothelial dysfunction contributes to the pathophysiology of dilated cardiomyopathy (DCM). Allogeneic but not autologous mesenchymal stem cells (MSCs) improve endothelial function in DCM patients. We hypothesized that these effects are modulated by release of stromal derived factor-1α (...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Premer, Courtney, Wanschel, Amarylis, Porras, Valeria, Balkan, Wayne, Legendre-Hyldig, Tatiana, Saltzman, Russell G., Dong, Chunming, Schulman, Ivonne Hernandez, Hare, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769040/
https://ncbi.nlm.nih.gov/pubmed/31616309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01182
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