Mesenchymal Stem Cell Secretion of SDF-1α Modulates Endothelial Function in Dilated Cardiomyopathy

BACKGROUND: Endothelial dysfunction contributes to the pathophysiology of dilated cardiomyopathy (DCM). Allogeneic but not autologous mesenchymal stem cells (MSCs) improve endothelial function in DCM patients. We hypothesized that these effects are modulated by release of stromal derived factor-1α (...

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Udgivet i:Front Physiol
Main Authors: Premer, Courtney, Wanschel, Amarylis, Porras, Valeria, Balkan, Wayne, Legendre-Hyldig, Tatiana, Saltzman, Russell G., Dong, Chunming, Schulman, Ivonne Hernandez, Hare, Joshua M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769040/
https://ncbi.nlm.nih.gov/pubmed/31616309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01182
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