Mesenchymal Stem Cell Secretion of SDF-1α Modulates Endothelial Function in Dilated Cardiomyopathy

BACKGROUND: Endothelial dysfunction contributes to the pathophysiology of dilated cardiomyopathy (DCM). Allogeneic but not autologous mesenchymal stem cells (MSCs) improve endothelial function in DCM patients. We hypothesized that these effects are modulated by release of stromal derived factor-1α (...

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Publicat a:Front Physiol
Autors principals: Premer, Courtney, Wanschel, Amarylis, Porras, Valeria, Balkan, Wayne, Legendre-Hyldig, Tatiana, Saltzman, Russell G., Dong, Chunming, Schulman, Ivonne Hernandez, Hare, Joshua M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769040/
https://ncbi.nlm.nih.gov/pubmed/31616309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01182
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