Genetic determinants of responsiveness to mesenchymal stem cell injections in non-ischemic dilated cardiomyopathy

BACKGROUND: Non-ischemic dilated cardiomyopathy (NIDCM) responds variably to intramyocardial injection of mesenchymal stem cells (MSCs). We hypothesized that NIDCM genotype may influence responsiveness to MSC therapy and performed genotyping on all patients in the POSEIDON-DCM trial. METHODS: POSEID...

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Udgivet i:EBioMedicine
Main Authors: Rieger, Angela C., Myerburg, Robert J., Florea, Victoria, Tompkins, Bryon A., Natsumeda, Makoto, Premer, Courtney, Khan, Aisha, Schulman, Ivonne H., Vidro-Casiano, Mayra, DiFede, Darcy L., Heldman, Alan W., Mitrani, Raul, Hare, Joshua M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838383/
https://ncbi.nlm.nih.gov/pubmed/31648988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.043
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