Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry

BACKGROUND: We previously conducted a systematic field synopsis of 1059 breast cancer candidate gene studies and investigated 279 genetic variants, 51 of which showed associations. The major limitation of this work was the small sample size, even pooling data from all 1059 studies. Thereafter, genom...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Yang, Yaohua, Shu, Xiang, Shu, Xiao-ou, Bolla, Manjeet K., Kweon, Sun-Seog, Cai, Qiuyin, Michailidou, Kyriaki, Wang, Qin, Dennis, Joe, Park, Boyoung, Matsuo, Keitaro, Kwong, Ava, Park, Sue Kyung, Wu, Anna H., Teo, Soo Hwang, Iwasaki, Motoki, Choi, Ji-Yeob, Li, Jingmei, Hartman, Mikael, Shen, Chen-Yang, Muir, Kenneth, Lophatananon, Artitaya, Li, Bingshan, Wen, Wanqing, Gao, Yu-Tang, Xiang, Yong-Bing, Aronson, Kristan J., Spinell, John J., Gago-Dominguez, Manuela, John, Esther M., Kurian, Allison W., Chang-Claude, Jenny, Chen, Shou-Tung, Dörk, Thilo, Evans, D. Gareth R., Schmidt, Marjanka K., Shin, Min-Ho, Giles, Graham G., Milne, Roger L., Simard, Jacques, Kubo, Michiaki, Kraft, Peter, Kang, Daehee, Easton, Douglas F., Zheng, Wei, Long, Jirong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838373/
https://ncbi.nlm.nih.gov/pubmed/31629678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.09.006
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