Genetically Predicted Levels of DNA Methylation Biomarkers and Breast Cancer Risk: Data From 228 951 Women of European Descent

BACKGROUND: DNA methylation plays a critical role in breast cancer development. Previous studies have identified DNA methylation marks in white blood cells as promising biomarkers for breast cancer. However, these studies were limited by low statistical power and potential biases. Using a new method...

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Publicat a:J Natl Cancer Inst
Autors principals: Yang, Yaohua, Wu, Lang, Shu, Xiao-Ou, Cai, Qiuyin, Shu, Xiang, Li, Bingshan, Guo, Xingyi, Ye, Fei, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Andrulis, Irene L, Brenner, Hermann, Chenevix-Trench, Georgia, Campa, Daniele, Castelao, Jose E, Gago-Dominguez, Manuela, Dörk, Thilo, Hollestelle, Antoinette, Lophatananon, Artitaya, Muir, Kenneth, Neuhausen, Susan L, Olsson, Håkan, Sandler, Dale P, Simard, Jacques, Kraft, Peter, Pharoah, Paul D P, Easton, Douglas F, Zheng, Wei, Long, Jirong
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073907/
https://ncbi.nlm.nih.gov/pubmed/31143935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz109
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