Biochemical characterization and chemical validation of Leishmania MAP Kinase-3 as a potential drug target

Protozoan parasites of the Leishmania genus have evolved unique signaling pathways that can sense various environmental changes and trigger stage differentiation for survival and host infectivity. MAP kinase (MAPK) plays a critical role in various cellular activities like cell differentiation, proli...

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Vydáno v:Sci Rep
Hlavní autoři: Raj, Shweta, Saha, Gundappa, Sasidharan, Santanu, Dubey, Vikash Kumar, Saudagar, Prakash
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838069/
https://ncbi.nlm.nih.gov/pubmed/31700105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52774-6
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