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Identification of lead molecules against potential drug target protein MAPK4 from L. donovani: An in-silico approach using docking, molecular dynamics and binding free energy calculation

Leishmaniasis caused by obligate intracellular parasites of genus Leishmania is one of the most neglected tropical diseases threatening 350 million people worldwide. Protein kinases have drawn much attention as potential drug targets due to their important role in various cellular processes. In Leis...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raj, Shweta, Sasidharan, Santanu, Dubey, Vikash Kumar, Saudagar, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699710/
https://ncbi.nlm.nih.gov/pubmed/31425543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221331
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