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Novel Agents against Miltefosine-Unresponsive Leishmania donovani

Visceral leishmaniasis is a deadly endemic disease. Unresponsiveness to the only available oral drug miltefosine poses a big challenge for the chemotherapy of the disease. We report a novel molecule, PS-203 {4-(4,4,8-trimethyl-7-oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic acid methyl ester}, as effecti...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Das, Mousumi, Saha, Gundappa, Saikia, Anil K., Dubey, Vikash Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649250/
https://ncbi.nlm.nih.gov/pubmed/26392497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00928-15
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