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Tyr(740) and Tyr(751) residues of platelet-derived growth factor beta receptor are responsible for the redox regulation of phosphatase and tensin homolog in the cells stimulated with platelet-derived growth factor
Exposure of cells to hydrogen peroxide or platelet-derived growth factor (PDGF) induced Akt phosphorylation and oxidation of phosphatase and tensin homolog (PTEN). The Cys(124) and Cys(71) residues of PTEN were critical for the formation of a disulfide bond and the intermediate glutathionylation in...
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| Pubblicato in: | Redox Rep |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6837401/ https://ncbi.nlm.nih.gov/pubmed/21888769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/1351000211Y.0000000005 |
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