Lipid droplet‐dependent fatty acid metabolism controls the immune suppressive phenotype of tumor‐associated macrophages

Tumor‐associated macrophages (TAMs) promote tumor growth and metastasis by suppressing tumor immune surveillance. Herein, we provide evidence that the immunosuppressive phenotype of TAMs is controlled by long‐chain fatty acid metabolism, specifically unsaturated fatty acids, here exemplified by olea...

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Détails bibliographiques
Publié dans:EMBO Mol Med
Auteurs principaux: Wu, Hao, Han, Yijie, Rodriguez Sillke, Yasmina, Deng, Hongzhang, Siddiqui, Sophiya, Treese, Christoph, Schmidt, Franziska, Friedrich, Marie, Keye, Jacqueline, Wan, Jiajia, Qin, Yue, Kühl, Anja A, Qin, Zhihai, Siegmund, Britta, Glauben, Rainer
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835560/
https://ncbi.nlm.nih.gov/pubmed/31602788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910698
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