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Lipid droplet‐dependent fatty acid metabolism controls the immune suppressive phenotype of tumor‐associated macrophages

Tumor‐associated macrophages (TAMs) promote tumor growth and metastasis by suppressing tumor immune surveillance. Herein, we provide evidence that the immunosuppressive phenotype of TAMs is controlled by long‐chain fatty acid metabolism, specifically unsaturated fatty acids, here exemplified by olea...

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Bibliografske podrobnosti
izdano v:EMBO Mol Med
Main Authors: Wu, Hao, Han, Yijie, Rodriguez Sillke, Yasmina, Deng, Hongzhang, Siddiqui, Sophiya, Treese, Christoph, Schmidt, Franziska, Friedrich, Marie, Keye, Jacqueline, Wan, Jiajia, Qin, Yue, Kühl, Anja A, Qin, Zhihai, Siegmund, Britta, Glauben, Rainer
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835560/
https://ncbi.nlm.nih.gov/pubmed/31602788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910698
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