Lipid droplet‐dependent fatty acid metabolism controls the immune suppressive phenotype of tumor‐associated macrophages

Tumor‐associated macrophages (TAMs) promote tumor growth and metastasis by suppressing tumor immune surveillance. Herein, we provide evidence that the immunosuppressive phenotype of TAMs is controlled by long‐chain fatty acid metabolism, specifically unsaturated fatty acids, here exemplified by olea...

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Pubblicato in:EMBO Mol Med
Autori principali: Wu, Hao, Han, Yijie, Rodriguez Sillke, Yasmina, Deng, Hongzhang, Siddiqui, Sophiya, Treese, Christoph, Schmidt, Franziska, Friedrich, Marie, Keye, Jacqueline, Wan, Jiajia, Qin, Yue, Kühl, Anja A, Qin, Zhihai, Siegmund, Britta, Glauben, Rainer
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835560/
https://ncbi.nlm.nih.gov/pubmed/31602788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910698
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