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Reduced Fitness Costs of mcr-1.2 Compared to Mutated pmrB in Isogenic Colistin-Resistant KPC-3-Producing Klebsiella pneumoniae

In the present study, we provide the results of a detailed genomic analysis and the growth characteristics of a colistin-resistant KPC-3-producing Klebsiella pneumoniae sequence type 512 (ST512) isolate (the colR-KPC3-KP isolate) with a mutated pmrB and isogenic isolates of colR-KPC3-KP with mcr-1.2...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Giordano, Cesira, Klak, Adrian, Barnini, Simona, Chlebowicz, Monika A., Menconi, Mariacristina, Rossen, John W., Friedrich, Alexander W., Bathoorn, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835208/
https://ncbi.nlm.nih.gov/pubmed/31694895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00551-19
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