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3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

Caloric restriction mimetics (CRMs) are natural or synthetic compounds that mimic the health‐promoting and longevity‐extending effects of caloric restriction. CRMs provoke the deacetylation of cellular proteins coupled to an increase in autophagic flux in the absence of toxicity. Here, we report the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Mol Med
Prif Awduron: Chen, Guo, Xie, Wei, Nah, Jihoon, Sauvat, Allan, Liu, Peng, Pietrocola, Federico, Sica, Valentina, Carmona‐Gutierrez, Didac, Zimmermann, Andreas, Pendl, Tobias, Tadic, Jelena, Bergmann, Martina, Hofer, Sebastian J, Domuz, Lana, Lachkar, Sylvie, Markaki, Maria, Tavernarakis, Nektarios, Sadoshima, Junichi, Madeo, Frank, Kepp, Oliver, Kroemer, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835206/
https://ncbi.nlm.nih.gov/pubmed/31609086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910469
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