3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

Abstract Caloric restriction mimetics (CRMs) are natural or synthetic compounds that mimic the health‐promoting and longevity‐extending effects of caloric restriction. CRMs provoke the deacetylation of cellular proteins coupled to an increase in autophagic flux in the absence of toxicity. Here, we r...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Guo Chen, Wei Xie, Jihoon Nah, Allan Sauvat, Peng Liu, Federico Pietrocola, Valentina Sica, Didac Carmona‐Gutierrez, Andreas Zimmermann, Tobias Pendl, Jelena Tadic, Martina Bergmann, Sebastian J Hofer, Lana Domuz, Sylvie Lachkar, Maria Markaki, Nektarios Tavernarakis, Junichi Sadoshima, Frank Madeo, Oliver Kepp, Guido Kroemer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Nature 2019-10-01
Serie:EMBO Molecular Medicine
Soggetti:
caloric restriction
caloric restriction mimetic
cardioprotection
TFE3
TFEB
Accesso online:https://doi.org/10.15252/emmm.201910469
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi