3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

Caloric restriction mimetics (CRMs) are natural or synthetic compounds that mimic the health‐promoting and longevity‐extending effects of caloric restriction. CRMs provoke the deacetylation of cellular proteins coupled to an increase in autophagic flux in the absence of toxicity. Here, we report the...

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Publicado en:EMBO Mol Med
Main Authors: Chen, Guo, Xie, Wei, Nah, Jihoon, Sauvat, Allan, Liu, Peng, Pietrocola, Federico, Sica, Valentina, Carmona‐Gutierrez, Didac, Zimmermann, Andreas, Pendl, Tobias, Tadic, Jelena, Bergmann, Martina, Hofer, Sebastian J, Domuz, Lana, Lachkar, Sylvie, Markaki, Maria, Tavernarakis, Nektarios, Sadoshima, Junichi, Madeo, Frank, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835206/
https://ncbi.nlm.nih.gov/pubmed/31609086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910469
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