Structural Features of a Conformation-dependent Antigen Epitope on ORFV-B2L Recognized by the 2E4 mAb

Previously, we successfully prepared a monoclonal antibody (mAb) named 2E4, that directly recognizes the major envelope protein B2L of the orf virus (ORFV), but there is little information about its epitope. Here, we meticulously mapped the 2E4 epitope through combinatorial programs and identified t...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yu, Yongzhong, Zhao, Wenbo, Tan, Qiang, Zhang, Xue, Wang, Mengyao, Duan, Xuyang, Liu, Yuanyuan, Wu, Zhijun, Ma, Jinzhu, Song, Baifen, Zhao, Rui, Zhao, Kui, Lian, Zhengxing, Cui, Yudong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834619/
https://ncbi.nlm.nih.gov/pubmed/31695071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52446-5
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