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Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo

Integrative analyses that summarize and link molecular data to treatment sensitivity are crucial to capture the biological complexity which is essential to further precision medicine. We introduce Weighted Orthogonal Nonnegative parallel factor analysis (WON-PARAFAC), a data integration method that...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Yongsoo, Bismeijer, Tycho, Zwart, Wilbert, Wessels, Lodewyk F. A., Vis, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834616/
https://ncbi.nlm.nih.gov/pubmed/31695042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13027-2
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