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A multilevel pan-cancer map links gene mutations to cancer hallmarks

BACKGROUND: A central challenge in cancer research is to create models that bridge the gap between the molecular level on which interventions can be designed and the cellular and tissue levels on which the disease phenotypes are manifested. This study was undertaken to construct such a model from fu...

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Detalhes bibliográficos
Publicado no:Chin J Cancer
Main Authors: Knijnenburg, Theo A., Bismeijer, Tycho, Wessels, Lodewyk F. A., Shmulevich, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593384/
https://ncbi.nlm.nih.gov/pubmed/26369414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-015-0050-6
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