Identifying Drug Sensitivity Subnetworks with NETPHIX

Phenotypic heterogeneity in cancer is often caused by different patterns of genetic alterations. Understanding such phenotype-genotype relationships is fundamental for the advance of personalized medicine. We develop a computational method, named NETPHIX (NETwork-to-PHenotype association with eXclus...

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發表在:iScience
Main Authors: Kim, Yoo-Ah, Sarto Basso, Rebecca, Wojtowicz, Damian, Liu, Amanda S., Hochbaum, Dorit S., Vandin, Fabio, Przytycka, Teresa M.
格式: Artigo
語言:Inglês
出版: Elsevier 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566085/
https://ncbi.nlm.nih.gov/pubmed/33089107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101619
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