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Efficient algorithms to discover alterations with complementary functional association in cancer

Recent large cancer studies have measured somatic alterations in an unprecedented number of tumours. These large datasets allow the identification of cancer-related sets of genetic alterations by identifying relevant combinatorial patterns. Among such patterns, mutual exclusivity has been employed b...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Sarto Basso, Rebecca, Hochbaum, Dorit S., Vandin, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550413/
https://ncbi.nlm.nih.gov/pubmed/31120875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006802
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