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Beneficial effects of PGC-1α in the substantia nigra of a mouse model of MPTP-induced dopaminergic neurotoxicity
Background: Mitochondrial dysfunction and oxidative stress are closely associated with the pathogenesis of Parkinson’s disease. Peroxisome proliferator-activated receptor γ coactivator 1 alpha (PGC-1α) is thought to play multiple roles in the regulation of mitochondrial biogenesis and cellular energ...
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| Publicat a: | Aging (Albany NY) |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6834419/ https://ncbi.nlm.nih.gov/pubmed/31634150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102357 |
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