Mitochondrial Effects of PGC-1alpha Silencing in MPP(+) Treated Human SH-SY5Y Neuroblastoma Cells

The dopaminergic neuron degeneration and loss that occurs in Parkinson’s disease (PD) has been tightly linked to mitochondrial dysfunction. Although the aged-related cause of the mitochondrial defect observed in PD patients remains unclear, nuclear genes are of potential importance to mitochondrial...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Ye, Qinyong, Chen, Chun, Si, Erwang, Cai, Yousheng, Wang, Juhua, Huang, Wanling, Li, Dongzhu, Wang, Yingqing, Chen, Xiaochun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447087/
https://ncbi.nlm.nih.gov/pubmed/28611589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00164
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