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Inhibition of Hepatotoxicity by a LXR Inverse Agonist in a Model of Alcoholic Liver Disease

[Image: see text] Alcohol abuse is a major cause of liver disease and mortality worldwide and is a significant public health issue. Patients with alcoholic liver disease (ALD) have severe hepatic lipid accumulation, inflammation, and fibrosis. Therapies for ALD are very limited and even abstinence f...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Sengupta, Monideepa, Griffett, Kristine, Flaveny, Colin A., Burris, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834356/
https://ncbi.nlm.nih.gov/pubmed/31696159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00003
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