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Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease
The liver X receptor (LXR) functions as a receptor for oxysterols and plays a critical role in the regulation of glucose and lipid metabolism. We recently described a synthetic LXR inverse agonist that displayed efficacy in treatment of hepatic steatosis in a mouse model of non-alcoholic fatty liver...
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| Gepubliceerd in: | Biochem Biophys Res Commun |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087326/ https://ncbi.nlm.nih.gov/pubmed/27680310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.09.036 |
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