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REV-ERB agonism improves liver pathology in a mouse model of NASH

Non-alcoholic fatty liver disease (NAFLD) affects a significant number of people worldwide and currently there are no pharmacological treatments. NAFLD often presents with obesity, insulin resistance, and in some cases cardiovascular diseases. There is a clear need for treatment options to alleviate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Griffett, Kristine, Bedia-Diaz, Gonzalo, Elgendy, Bahaa, Burris, Thomas P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529425/
https://ncbi.nlm.nih.gov/pubmed/33002003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236000
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