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Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells

Excess dietary cholesterol intake and the dysregulation of cholesterol metabolism are associated with the pathogenesis and progression of nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and fibrosis. Hepatic accumulation of free cholesterol induces activation of nonparenchymal cells,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Endo-Umeda, Kaori, Makishima, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834202/
https://ncbi.nlm.nih.gov/pubmed/31614590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205045
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