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Liver X receptors regulate hepatic F4/80(+)CD11b(+) Kupffer cells/macrophages and innate immune responses in mice

The liver X receptors (LXRs), LXRα and LXRβ, are nuclear receptors that regulate lipid homeostasis. LXRs also regulate inflammatory responses in cultured macrophages. However, the role of LXRs in hepatic immune cells remains poorly characterized. We investigated the role of LXRs in regulation of inf...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Endo-Umeda, Kaori, Nakashima, Hiroyuki, Komine-Aizawa, Shihoko, Umeda, Naoki, Seki, Shuhji, Makishima, Makoto
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006359/
https://ncbi.nlm.nih.gov/pubmed/29915246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27615-7
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