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Liver X receptors regulate hepatic F4/80(+)CD11b(+) Kupffer cells/macrophages and innate immune responses in mice

The liver X receptors (LXRs), LXRα and LXRβ, are nuclear receptors that regulate lipid homeostasis. LXRs also regulate inflammatory responses in cultured macrophages. However, the role of LXRs in hepatic immune cells remains poorly characterized. We investigated the role of LXRs in regulation of inf...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Endo-Umeda, Kaori, Nakashima, Hiroyuki, Komine-Aizawa, Shihoko, Umeda, Naoki, Seki, Shuhji, Makishima, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006359/
https://ncbi.nlm.nih.gov/pubmed/29915246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27615-7
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