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Liver X receptors regulate hepatic F4/80(+)CD11b(+) Kupffer cells/macrophages and innate immune responses in mice

The liver X receptors (LXRs), LXRα and LXRβ, are nuclear receptors that regulate lipid homeostasis. LXRs also regulate inflammatory responses in cultured macrophages. However, the role of LXRs in hepatic immune cells remains poorly characterized. We investigated the role of LXRs in regulation of inf...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Endo-Umeda, Kaori, Nakashima, Hiroyuki, Komine-Aizawa, Shihoko, Umeda, Naoki, Seki, Shuhji, Makishima, Makoto
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006359/
https://ncbi.nlm.nih.gov/pubmed/29915246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27615-7
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