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Toward the computational design of protein crystals with improved resolution

Substantial advances have been made in the computational design of protein interfaces over the last 20 years. However, the interfaces targeted by design have typically been stable and high-affinity. Here, we report the development of a generic computational design method to stabilize the weak intera...

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Bibliografiske detaljer
Udgivet i:Acta Crystallogr D Struct Biol
Main Authors: Jeliazkov, Jeliazko R., Robinson, Aaron C., García-Moreno E., Bertrand, Berger, James M., Gray, Jeffrey J.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834074/
https://ncbi.nlm.nih.gov/pubmed/31692475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798319013226
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